Atracurium is an intermediate-acting nondepolarizing Neuromuscular Blocker. Routinely is used for the neuromuscular blockade in most pediatric surgeries. Cis-atracurium is an stereoisomer approximately 4 times as potent as atracurium. In contrast to atracurium, Cis-atracurium is devoid of chemically mediated histamine release.
During the COVID-19 pandemic there was a huge increase in the hospital use of these medicines for tracheal intubation.
INTERMEDIATES
1,5-Pentanediol (CAS 111-29-5)
Tetrahydropapaverine HCl (CAS 6429-04-5) – Atracurium
(R)-Tetrahydropapaverine HCl (CAS 54417-53-7) – Cis-Atracurium
KEY POINTS
• Reliable source, with broad experience in muscle relaxants
• GMP-like quality
• Competitive prices
• Good track record
MARKET
